Oxycodone/acetaminophen (Roxicet, Endocet, Percocet) is a moderately priced drug used to treat moderate to severe pain. This drug is more popular than comparable drugs. close What To Expect. Seeking addiction treatment can feel overwhelming. We know the struggle, which is why we're uniquely qualified to help. Your call is confidential, and there's no pressure to commit to treatment until you're ready. You can add Tylenol if you wish but i don't know about it increasing the effectiveness. Tylenol is pretty much useless for anything except fever reduction. hello there, i catched a flu with 39 ° fever,and i wonder how much dafalgan/tylenol is safe to take per day,when having cirrhosis. i had hep-c and did finished treatment before 5 months,4.5 months post tx i still was UND. When it comes to pain relief, there are several over-the-counter medications to choose from. Tylenol is a very popular pain relief medication that has been trusted for years. Yes, you can. The generally accepted maximum daily dose is 4 grams. In long term care 3 grams is often used as a safe cutoff. The manufacturer of the brand Tylenol recommends a 3 gram limit, likely due to patients not being aware of the acetaminophen found in so many OTC mixed products. Percocet (oxycodone and acetaminophen) is a combination drug consisting of an opioid and a pain reliever and fever reducer (analgesic and antipyretic) used for the management of moderate to severe pain, usually for an extended time period. Ok so percocet has tylonol in it and oxycodone does not. Vicodin is another type of pain medication, but is less strong then the other two. If I was to choose one it would definally be the oxycodone because it won't eat at your liver because no tylonol in it and taken for a longer period, that one is the best way to go. Use Only as Directed About 150 Americans a year die by accidentally taking too much acetaminophen, the active ingredient in Tylenol. The toll does not have to be so high. You can indeed take both of these medications at the same time, and in fact your doctor may recommend that you do so.